Effect of site of lactate infusion on regional lactate exchange in pigs
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چکیده
منابع مشابه
CRITICAL CARE Effect of site of lactate infusion on regional lactate exchange in pigs
Key points † This study addresses the uptake of lactate after central venous or portal infusion in pigs. † Lactate metabolism is important for understanding the haemodynamics and regional blood flow of sepsis. † Lactate infused into the portal vein is removed mainly by the liver, whereas central venous infusion results in less uptake by the liver. Background. The rate of extra-hepatic lactate p...
متن کاملEffect of site of lactate infusion on regional lactate exchange in pigs.
BACKGROUND The rate of extra-hepatic lactate production and the route of influx of lactate to the liver may influence both hepatic and extra-hepatic lactate exchange. We assessed the dose-response of hepatic and extra-hepatic lactate exchange during portal and central venous lactate infusion. METHODS Eighteen pigs randomly received either portal (n=5) or central venous (n=7) lactate infusion ...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2010
ISSN: 0007-0912
DOI: 10.1093/bja/aeq214